Intracerebroventricular

i.c.v.

Into the ventricles of the brain

Intra-arterial

i.a.

Into the lumen of an artery

Intracerebral

i.c.

Into the brain

Intradermal

i.d.

Into the dermal layer of the skin

Intramuscular

i.m.

Into a skeletal muscle

Intragastric

i.g.

Into the stomach

Intraperitoneal

i.p.

Into the peritoneum (body cavity)

Intravenous

i.v.

Into a vein

Oral

p.o.

By mouth

Subcutaneous

s.c.

Under the skin

quaque die (Latin)

q.d.

once a day

bis in die (Latin)

b.i.d.

twice a day

ter in die (Latin)

t.i.d.

three times a day

Abl

V-abl Abelson murine leukemia viral   oncogene homolog 1

ALK

anaplastic lymphoma kinase

ATM

Ataxia telangiectasia mutated

B-Raf

B-Raf proto-oncogene   serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma   viral oncogene homolog B1

Bcl-2

B-cell lymphoma 2

Bcr

breakpoint cluster region

Caspases

cysteine-aspartic proteases or   cysteine-dependent aspartate-directed proteases

CCR5

co-receptors chemokine receptor 5

CDK

Cyclin-dependent kinase

CFTR potentiator

Cystic fibrosis transmembrane   conductance regulator

CTSK

Cathepsin K

c-Kit

CD117 (cluster of differentiation   117), also called KIT or C-kit receptor

c-Met

mesenchymal-epithelial transition

DNA-PK

DNA-dependent protein kinase

DPP-4

Dipeptidyl peptidase-4

EGFR

Epidermal growth factor receptor

Factor Xa

Stuart-Prower factor, an enzyme of   the coagulation cascade

FGFR

Fibroblast growth factor receptor

FLT-3

fms-like tyrosine kinase-3

FTS

Farnesyl thiosalicylic acid

GSK-3

Glycogen synthase kinase 3

HER2

Human epidermal growth factor   receptor 2

HDAC

Histone deacetylase

HIF

Hypoxia-inducible factor

HSP-70

heat-shock protein-70

HSP-90

heat-shock protein-90

IGF-1R

Insulin-like growth factor 1   receptor

JAK

Janus kinase

JNK

c-Jun N-terminal kinases

Ksp

Kinesin spindle protein

MAPK

Mitogen-activated Protein Kinase

MEK

MAPK/ERK kinase

mGluRs

metabotropic glutamate receptors

mTOR

Mammalian target of rapamycin

NF-kB

Nuclear factor-κB

p38 MAPK

p38 Mitogen-activated Protein Kinase

p53

protein 53 or tumor protein 53

PARP

Poly (ADP-ribose) polymerase

PDGFR

platelet-derived growth factor   receptor

PDK-1

phosphoinositide-dependent kinase-1

Rho

ρ factor

PI3K

Phosphatidylinositol 3-kinases

PKC

protein kinase C

PLK

Polo-like kinase

Ras

renin-angiotensin system

RNAP

RNA Polymerase or RNApol

S1PR1

Sphingosine-1-phosphate receptor   (S1P1) also known as endothelial differentiation gene 1 (EDG1)

sPLA2

Secreted phospholipase A2

Src

Rous sarcoma oncogene cellular   homolog

Stat

Signal Transducers and Activator of   Transcription

Survivin

baculoviral inhibitor of apoptosis   repeat-containing 5 or BIRC5

TGF

Transforming growth factor

TNF

Tumor necrosis factor

VEGFR

Vascular Endothelial Growth Factor   Receptor

Wnt

a portmanteau of int and Wg and   stands for "Wingless-related integration site"