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Resatorvid (TAK-242; CLI-095)

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Catalog No：CL1002 CAS No.：243984-11-4 MDLNo： Formula：C15H17ClFNO4S MW：361.82

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Product Overview

Product Name	Resatorvid (TAK-242; CLI-095)
CAS	243984-11-4
Formula	C15H17ClFNO4S
MW	361.82
Appearance	Off-white to yellow solid
Storage condition	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Product details

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.

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CL1002

Resatorvid (TAK-242; CLI-095)

243984-11-4 98+%