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Laduviglusib (CHIR-99021; CT99021)

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Catalog No：CL1006 CAS No.：252917-06-9 MDLNo： Formula：C22H18Cl2N8 MW： 465.34

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
10 mg	In-stock	$300.00	Visible after login	- +
25 mg	In-stock	$500.00	Visible after login	- +
50 mg	In-stock	$800.00	Visible after login	- +
100 mg	In-stock	$1500.00	Visible after login	- +

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Product Overview

Product Name	Laduviglusib (CHIR-99021; CT99021)
CAS	252917-06-9
Formula	C22H18Cl2N8
MW	465.34
Appearance	Off-white to light brown powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

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化学稳定性	DMSO中的溶液可在-20°下稳定储存3个月。

Product details

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.

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CL1006

Laduviglusib (CHIR-99021; CT99021)

252917-06-9 99+%