Y-27632
Y-27632 (free base)
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Product Overview
Product Name Y-27632 (free base)
CAS146986-50-7
FormulaC14H21N3O
MW247.34
AppearanceWhite to off-white powder
Storage condition-20°C, protect from light, stored under nitrogen
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Product details

Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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Related
Y27632 HCl hydrate | (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate | Y-27632 Dihydrochloride Monohydrate
Y-27632 Dihydrochloride (Synonyms: Y-27632 2HCl ; trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride)
History
Gliquidone (Synonyms: AR-DF 26)
INT-777 | S-EMCA | INT 777
Y-27632 (free base)
Limaprost (Synonyms: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206)
MTSSL (Synonyms: (1-Oxyl-2,2,5,5-tetramethyl-∆3-pyrroline-3-methyl) Methanethiosulfonate; Otmpmms)
5-ALA (Synonyms: 5-Aminolevulinic Acid Phosphate; 5-Amino-4-oxopentanoic acid phosphate)
KAAD-Cyclopamine (Synonyms: Cyclopamine-KAAD;3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine)
Etoposide (Synonyms: VP-16; VP-16-213;VP-16213)
DL-Glutamic Acid Monohydrate
Reparixin (Synonyms: Repertaxin; DF 1681Y)