Y-27632
Y-27632 (free base)
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Product Overview
Product Name Y-27632 (free base)
CAS146986-50-7
FormulaC14H21N3O
MW247.34
AppearanceWhite to off-white powder
Storage condition-20°C, protect from light, stored under nitrogen
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Product details

Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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Related
Y27632 HCl hydrate | (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate | Y-27632 Dihydrochloride Monohydrate
Y-27632 Dihydrochloride (Synonyms: Y-27632 2HCl ; trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride)
History
Y-27632 (free base)
Talabostat Mesylate | Val-boroPro mesylate | PT100 mesylate
4-Amino-1-benzylpiperidine-4-carboxylic acid
Anti-Human IGF1RxHer3 Bispecific Antibody (Istiratumab; MM 141; MM-005)