(E)-4-羟基他莫昔芬
(E)-4-Hydroxytamoxifen; (E)-Afimoxifene
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Product Overview
Product Name (E)-4-Hydroxytamoxifen; (E)-Afimoxifene
CAS174592-47-3
FormulaC26H29NO2
MW387.51
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
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Afimoxifene, E-isomer, also called (E)-4-Hydroxytamoxifen, is a SERM and active metabolite of tamoxifen. The E isomer is less active thatn the Z isomer. It induces autophagy, vacuole formation and KRAS degradation in cancerl cells and decreases contractility in myocytes.

Related literature
Related
(Z)-4-Hydroxytamoxifen (Synonyms:(Z)-4-OHT; 4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene;4-Monohydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol)
History
(E)-4-Hydroxytamoxifen; (E)-Afimoxifene
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