(E)-4-羟基他莫昔芬
(E)-4-Hydroxytamoxifen; (E)-Afimoxifene
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name (E)-4-Hydroxytamoxifen; (E)-Afimoxifene
CAS174592-47-3
FormulaC26H29NO2
MW387.51
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Security information
Product details

Afimoxifene, E-isomer, also called (E)-4-Hydroxytamoxifen, is a SERM and active metabolite of tamoxifen. The E isomer is less active thatn the Z isomer. It induces autophagy, vacuole formation and KRAS degradation in cancerl cells and decreases contractility in myocytes.

Related literature
Related
(Z)-4-Hydroxytamoxifen (Synonyms:(Z)-4-OHT; 4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene;4-Monohydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol)
History
(E)-4-Hydroxytamoxifen; (E)-Afimoxifene
Boc-Gln(Trt)-OH
Cefmetazole | CS 1170
(E/Z)-Afatinib (Synonyms: (E/Z)-BIBW 2992)
Cinacalcet hydrochloride (Synonyms: Cinacalcet (AMG-073) HCl; AMG-073 hydrochloride)
(R)-Cyclopropyl(4-fluorophenyl)methanamine hydrochloride
Secretin Acetate
Sanggenon N
Crizotinib hydrochloride | PF-02341066 hydrochloride
Tolterodine Tartrate (Synonyms: Kabi-2234; PNU-200583E)