氨磷汀
Amifostine (Synonyms: WR2721)
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name Amifostine (Synonyms: WR2721)
CAS20537-88-6
FormulaC5H15N2O3PS
MW214.22
MDLMFCD00233058
AppearanceWhite to off-white powder
Storage conditionPowder -20°C3 years ; 4°C 2 years ;| In solvent -80°C 6 months ; -20°C 1 month
Security information
Product details

Amifostine (WR2721) is a potent cytoprotective and radioprotective agent, selectively safeguarding normal tissues from chemotherapy and radiation-induced damage. It acts as a prodrug, activating to WR-1065 by alkaline phosphatase, which scavenges free radicals and protects cells. Amifostine also induces HIF-α1 and p53, key regulators in the cellular response to hypoxia and DNA damage. Its antiangiogenic properties, by modulating VEGF-A, suggest potential in inhibiting tumor vasculature. Recent studies highlight its renal toxicity reduction and explore PEGylation to enhance safety and efficacy, making Amifostine a versatile protector in cancer therapies.
Tags: buy Amifostine | purchase Amifostine | Amifostine cost | order Amifostine | Amifostine chemical structure | Amifostine formula | Amifostine molecular weight


Related
Amifostine Trihydrate (Synonyms: WR2721 trihydrate)
History
Pranoprofen
Torin 1
XAV-939
Ifenprodil tartrate (Synonyms: Ifenprodil hemitartrate;NP-120 tartrate; RC-61-91 tartrate;Ifenprodil (+)-tartrate salt;α-(4-Hydroxyphenyl)-β-methyl-4-benzyl-1-piperidineethanol (+)-tartrate salt)
Zafirlukast (Synonyms: ICI 204219)
Amifostine (Synonyms: WR2721)
Dexrazoxane Hydrochloride | Dexrazoxane HCl | ADR-529 HCl, ICRF-187 HCl
Lorcaserin Hydrochloride | APD356
Ramoplanin | A-16686 | MDL 62198
Werner syndrome RecQ helicase-IN-1 sodium (EX-A7900;G65952); N-(2-Chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide, sodium salt