(Z)-3-(((4-(N-甲基-2-(4-甲基哌嗪-1-基)乙酰氨基)苯基)氨基)(苯基)亚甲基)-2-氧代吲哚啉-6-羧酸甲酯; 尼达尼布
Nintedanib (Synonyms: BIBF 1120; Intedanib)
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Size
500 mg 1 g
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In-stock
Price
$336.00
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Product Availability
In-stock
Price
$498.00
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Product Overview
Product Name Nintedanib (Synonyms: BIBF 1120; Intedanib)
CAS656247-17-5
FormulaC31H33N5O4
MW539.62
MDLMFCD11974012
AppearanceYellow crystalline powder
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Product details

Nintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptor (PDGFR). Intedanib selectively binds to and inhibits vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet-derived growth factor receptor (PDGFR) tyrosine kinases, which may result in the induction of endothelial cell apoptosis; a reduction in tumor vasculature; and the inhibition of tumor cell proliferation and migration.
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Related
Nintedanib Ethanesulfonate Salt (Synonyms: Intedanib; BIBF 1120)
History
Nintedanib (Synonyms: BIBF 1120; Intedanib)