来那度胺
Lenalidomide | CC-5013
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
500 mg 1 g 5 g
Product Availability
In-stock
Price
$320.00
Member price
Product Availability
In-stock
Price
$400.00
Member price
Product Availability
In-stock
Price
$1200.00
Member price
Quantity
- +
Product Overview
Product Name Lenalidomide | CC-5013
CAS191732-72-6
FormulaC13H13N3O3
MW259.26
AppearanceOff-white to light yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.

Related literature
Related
Sorry, no related items
History
Lenalidomide | CC-5013
Carboplatin (Synonyms: NSC 241240; 卡铂)
Astragaloside IV
Miglustat (Synonyms: N-Butyldeoxynojirimycin; NB-DNJ; OGT 918)
Bempedoic Acid
Aristolactam FI | Piperolactam A
(S)-1-(2-Fluorophenyl)ethanamine
A68930 hydrochloride
Tiagabine hydrochloride | NO050328 hydrochloride | NO328 hydrochloride | TGB hydrochloride
Dexrazoxane Hydrochloride | Dexrazoxane HCl | ADR-529 HCl, ICRF-187 HCl