4-((2-氨基苯基)氨甲酰)苄基氨基甲酸3-吡啶基甲基酯; 恩替诺特
Entinostat (Synonyms: MS-275; SNDX-275)
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Product Overview
Product Name Entinostat (Synonyms: MS-275; SNDX-275)
CAS209783-80-2
FormulaC21H20N4O3
MW376.41
AppearanceYellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. 
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History
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