PD173074
PD173074
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Product Overview
Product Name PD173074
CAS219580-11-7
FormulaC28H41N7O3
MW523.67
AppearanceOff-white to yellow powder
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Product details

PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells

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History
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