Product Name | PD173074 |
---|---|
CAS | 219580-11-7 |
Formula | C28H41N7O3 |
MW | 523.67 |
Appearance | Off-white to yellow powder |
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells
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