索拉非尼
Sorafenib; BAY 43-9006; Sorafenib Base; Sorafenib Free Base
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500 mg 1 g
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$126.00
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$188.00
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Product Overview
Product Name Sorafenib; BAY 43-9006; Sorafenib Base; Sorafenib Free Base
CAS284461-73-0
FormulaC21H16ClF3N4O3
MW464.82
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Sorafenib (BAY549085; BAY-549085; BAY439006; BAY-439006; Nexavar; SFN) an approved anticancer medication, is a potent and orally bioavailable multikinase inhibitor with potential anticancer activity (BAY549085; BAY-549085; BAY439006; BAY-439006; Nexavar; SFN). In enzymatic assays, it inhibits numerous kinases, including Raf-1, B-Raf, and VEGFR-2, with IC50 values of 6 nM, 22 nM, and 90 nM, respectively. The FDA granted sorafenib approval in 2005 to treat advanced renal cancer.

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History
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