甲苯磺酸索拉非尼
Sorafenib Tosylate
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1 g 5 g
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$250.00
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$400.00
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Product Overview
Product Name Sorafenib Tosylate
CAS475207-59-1
FormulaC28H24ClF3N4O6S
MW637.03
MDLMFCD08235032
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2VEGFR-3PDGFR-βFlt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.

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History
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