AOH1996
AOH1996 | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
5 mg 10 mg 25 mg
Product Availability
In-stock
Price
$900.00
Member price
Product Availability
In-stock
Price
$1360.00
Member price
Product Availability
In-stock
Price
$2500.00
Member price
Quantity
- +
Product Overview
Product Name AOH1996 | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide
CAS2089314-64-5
FormulaC26H22N2O4
MW426.46
AppearanceWhite powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

AOH1996 is an inhibitor of proliferating cell nuclear antigen (PCNA).It binds to PCNA in a thermal shift assay. AOH1996 (500 nM) induces apoptosis in SK-N-DZ neuroblastoma cells but not 7SMOO32 normal neural crest stem cells. It induces DNA damage in SK-N-AS neuroblastoma cells expressing wild-type DNA-directed RNA polymerase II subunit RPB1 but not in SK-N-AS cells expressing RPB1Y418A. AOH1996 (40 mg/kg) decreases tumor volume in SK-N-BE(2)-C neuroblastoma, MDA-MB-468 breast cancer, and NCI H82 small cell lung cancer mouse xenograft models.

Related literature
Related
Sorry, no related items
History
Dovitinib Free Base/CHIR-258/TKI-258
Saquinavir Mesylate | Ro 31-8959/003
Luminol (Diogenes reagent)
AOH1996 | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide
Anti-Human PD-1xCTLA-4 Bispecific Antibody(Vudalimab;XmAb-20717,cytotoxic T-lymphocyte-associated protein 4, CD152;programmed cell death 1, PD1, PD-1, CD279)
Loxapine succinate salt
(S)-Timolol maleate | (S)-L-714,465 maleate | MK 950
MK-2894
Elacestrant (Synonyms: RAD1901)
Secaubryenol