GSK2656157 | GSK-2656157
GSK2656157 (Synonyms: GSK-2656157)
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Product Overview
Product Name GSK2656157 (Synonyms: GSK-2656157)
CAS1337532-29-2
FormulaC23H21FN6O
MW416.45
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases. GSK2656157 decreases apoptosis and inhibits excessive autophagy

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History
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