Product Name | LY2835219 free base | Abemaciclib | LY2835219 |
---|---|
CAS | 1231929-97-7 |
Formula | C27H32F2N8 |
MW | 506.59 |
Appearance | Off-white to yellow powder |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Abemaciclib (formerly known as LY2835219) is a potent and selective, and orally bioavailable dual inhibitor of CDK4 (cyclin-dependent kinase) and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.
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