Pyridostatin (RR82)
Pyridostatin (Synonyms: RR82)
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Product Name Pyridostatin (Synonyms: RR82)
CAS1085412-37-8
FormulaC31H32N8O5
MW596.64
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Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
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History
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