MMAF hydrochloride
MMAF Hydrochloride;Monomethylauristatin F Hydrochloride
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5 mg 10 mg 25 mg
Product Availability
3-5days
Price
$200.00
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Product Availability
3-5days
Price
$325.00
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Product Availability
3-5days
Price
$500.00
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Product Overview
Product Name MMAF Hydrochloride;Monomethylauristatin F Hydrochloride
CAS1415246-68-2
FormulaC39H66ClN5O8
MW768.42
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Monomethyl auristatin F (MMAF) HCl is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. Mafodotin is the term used in International Nonproprietary Names for MMAF-antibody-conjugates to describe MMAF along with its antibody-binding structure. As opposed to auristatin F, which has two methyl substituents in its N-terminal amino group, MMAF is actually desmethyl-auristatin F.

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