一甲基澳瑞他汀 E
Monomethyl auristatin E (Synonyms: MMAE; SGD-1010;Monomethylauristatin E)
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Product Name Monomethyl auristatin E (Synonyms: MMAE; SGD-1010;Monomethylauristatin E)
CAS474645-27-7
FormulaC39H67N5O7
MW717.98
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Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

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Monomethyl auristatin E (Synonyms: MMAE; SGD-1010;Monomethylauristatin E)