利克飞龙
Licofelone (Synonyms: ML-3000)
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Product Overview
Product Name Licofelone (Synonyms: ML-3000)
CAS156897-06-2
FormulaC23H22ClNO2
MW379.88
AppearanceOff-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.
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History
Licofelone (Synonyms: ML-3000)
Methylprednisolone (Synonyms: NSC-19987;U 7532)
SR-4835