替格鲁西布 | 泰格列净
Tideglusib (Synonyms: NP031112; NP-12)
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Product Overview
Product Name Tideglusib (Synonyms: NP031112; NP-12)
CAS865854-05-3
FormulaC19H14N2O2S
MW334.39
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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 Tideglusib, also known as NP031112, is a GSK-3 inhibitor, which is currently under clinical trial for Alzheimer's disease. Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial. Tideglusib prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders.

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History
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