乐伐替尼 | 仑伐替尼 | 乐法替尼 | E7080
Lenvatinib | E7080
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Product Overview
Product Name Lenvatinib | E7080
CAS417716-92-8
FormulaC21H19ClN4O4
MW426.85
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities.


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Lenvatinib Mesylate | E7080 mesylate | ER-203492-00
History
Lenvatinib | E7080
Abciximab
Namilumab (Anti-CSF2 / GM-CSF)
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1))
Theralizumab | TGN1412 | TAB-08 | TABO8
Opipramol (Synonyms: Ensidon; G-33040)
Pinobanksin 3-acetate ((2R,3R)-Pinobanksin 3-acetate; Pinobanksin 3-O-acetate; Pinobanksin acetate)
Anti-Human IL-23 Monoclonal Antibody(Guselkumab)
Alacizumab (Anti-VEGFR2 / KDR / CD309)
Benralizumab (Anti-IL-5Ra/ CD125)