乐伐替尼 | 仑伐替尼 | 乐法替尼 | E7080
Lenvatinib | E7080
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Product Overview
Product Name Lenvatinib | E7080
CAS417716-92-8
FormulaC21H19ClN4O4
MW426.85
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities.


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Lenvatinib Mesylate | E7080 mesylate | ER-203492-00
History
Mirdametinib (PD0325901)
Lenvatinib | E7080
Lucatumumab (Synonyms: HCD122)
Amphotericin B | NSC 527017 | LNS-AmB
Siplizumab (Synonyms: MEDI-507)
Pinatuzumab (Anti-Siglec-2 / CD22)
(±)-Stylopine hydrochloride | Tetrahydrocoptisine hydrochloride
Rosin
Nigakinone
Opipramol (Synonyms: Ensidon; G-33040)