1-(3-(叔丁基)-1-(对甲苯基)-1H-吡唑-5-基)-3-(4-(2-吗啉乙氧基)萘-1-基)脲; 达马莫德;度马莫德
Doramapimod (Synonyms: BIRB 796)
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Product Overview
Product Name Doramapimod (Synonyms: BIRB 796)
CAS285983-48-4
FormulaC31H37N5O3
MW527.66
MDLMFCD09752957
AppearanceOff-white to gray powder
Storage conditionStore short-term at 0-4°C or long-term at -20°C in a dry, dark place.
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Doramapimod (BIRB 796) is an orally active, potent inhibitor of p38 MAPK with IC50 values of p38α=38 nM, p38β=65 nM, p38γ=200 nM, and p38δ=520 nM. Doramapimod exhibits picomolar affinity (Kd=0.1 nM) for p38 kinase. Doramapimod also inhibits B-Raf and Abl with IC50 values of 83 nM and 14.6 μM, respectively.

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Doramapimod (Synonyms: BIRB 796)
Etanercept,stock solution