Product Name | Anastrozole |
---|---|
CAS | 120511-73-1 |
Formula | C17H19N5 |
MW | 293.37 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Anastrozole (formerly known as ZD-1033) is a potent, third-generation nonsteroidal and selective inhibitor of aromatase with an IC50 of 15 nM for inhibiting human placental aromatase. Anastrozole selectively binds to and reversibly inhibits aromatase, a cytochrome P-450 enzyme complex found in many tissues including those of the premenopausal ovary, liver, and breast. Anastrozole has been reported to inhibit human placental aromatase with an IC50 value of 14.6 nM or 0.0043μg/ml.
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