伊沙匹隆
Ixabepilone | BMS-247550 | Aza-epothilone B
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Product Overview
Product Name Ixabepilone | BMS-247550 | Aza-epothilone B
CAS219989-84-1
FormulaC27H42N2O5S
MW506.70
AppearanceWhite to off-white powder
Storage condition4°C, protect from light
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Product details

Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.


Related literature
https://doi.org/10.1158/1535-7163.MCT-08-0999
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History
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