Product Name | AEBSF HCl | AEBSF hydrochloride | 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride | 4-(2-Aminoethyl)benzenesulfonyl Fluoride Hydrochloride |
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CAS | 30827-99-7 |
Formula | C8H11ClFNO2S |
MW | 239.69 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
AEBSF is a specific irreversible serine protease inhibitor. AEBSF inhibits the rat embryo implantation in vivo and interferes with cell adhesion in vitro. Both AEBSF and PMSF are sulfonyl fluorides and are sulfonylating agents. Sulfonyl fluorides act by reacting with the hydroxy group of the active site serine residue to form a sulfonyl enzyme derivative. This derivative may be stable for long periods of time except at high pH.
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