Product Name | SB 271046 Hydrochloride | SB 271046A |
---|---|
CAS | 209481-24-3 |
Formula | C20H23Cl2N3O3S2 |
MW | 488.45 |
Storage condition | 4°C, sealed storage, away from moisture |
SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).
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