PNU-159682; PNU 159682
PNU-159682 (Synonyms: PNU 159682)
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Product Name PNU-159682 (Synonyms: PNU 159682)
CAS202350-68-3
FormulaC32H35NO13
MW641.62
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PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.
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History
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