(1R,2R,4S)-4-((R)-2-((3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-二羟基-10,21-二甲氧基-6,8,12,14,20,26-六甲基-1,5,11,28,29-五氧代-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-二十四氢-3H-23,27-环氧吡啶并[2,1-c][1]氮杂环三十一烷-3-基)丙基)-2-甲氧基环己基 二甲基亚膦酸酯
Ridaforolimus (Synonyms: MK-8669; Deforolimus; AP23573; 42-(二甲基亚膦酰)雷帕霉素)
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Product Name Ridaforolimus (Synonyms: MK-8669; Deforolimus; AP23573; 42-(二甲基亚膦酰)雷帕霉素)
CAS572924-54-0
FormulaC53 H84 N O14 P
MW990.21
MDLMFCD13184816
AppearanceWhite to light yellow powder
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Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells.


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Ridaforolimus (Synonyms: MK-8669; Deforolimus; AP23573; 42-(二甲基亚膦酰)雷帕霉素)