Product Name | Sivelestat | EI546 | LY544349 | ONO5046 |
---|---|
CAS | 127373-66-4 |
Formula | C20H22N2O7S |
MW | 434.46 |
Appearance | White to off-white powder |
Storage condition | 4°C, protect from light |
Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
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