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Etoricoxib (Synonyms: MK-663; MK-0663; L-791456; Tauxib)
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3-5days
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$100.00
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Product Availability
3-5days
Price
$163.00
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Product Availability
3-5days
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$213.00
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Product Overview
Product Name Etoricoxib (Synonyms: MK-663; MK-0663; L-791456; Tauxib)
CAS202409-33-4
FormulaC18H15ClN2O2S
MW358.84
AppearanceLight yellow to yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
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History
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