蒽[1,9-cd]吡唑-6(2H)-酮; 1,9-吡唑蒽酮; 吡唑并蒽酮
SP600125 (Synonyms: Nsc75890; SP 600125; Anthra[1,9-cd]pyrazol-6(2H)-one;1,9-Pyrazoloanthrone; Anthrapyrazolone)
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name SP600125 (Synonyms: Nsc75890; SP 600125; Anthra[1,9-cd]pyrazol-6(2H)-one;1,9-Pyrazoloanthrone; Anthrapyrazolone)
CAS129-56-6
FormulaC14H8N2O
MW220.23
MDLMFCD00022289
Security information
Product details

SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis.

Related literature
Related
Sorry, no related items
History
SP600125 (Synonyms: Nsc75890; SP 600125; Anthra[1,9-cd]pyrazol-6(2H)-one;1,9-Pyrazoloanthrone; Anthrapyrazolone)
Abituzumab (Anti-Integrin aV / ITGAV / CD51)
Oclacitinib Maleate (Synonyms: Oclacitinib monomaleate; PF-03394197 monomaleate;PF-03394197 Maleate)
Netarsudil dimesylate ( AR-13324 dimesylate)
IMP-1088
Methyl morpholine-3-carboxylate
BIX02188
Silydianin
(R)-Roscovitine (Synonyms: Seliciclib; CYC202,细胞周期蛋白B激酶抑制剂;塞利西利)
Fondaparinux Sodium (Synonyms: Fondaparin sodium; SR-90107A; Org 31540; Natural heparin pentasaccharide Sodium)