SB 408124
SB408124
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Product Overview
Product Name SB408124
CAS288150-92-5
FormulaC19H18F2N4O
MW356.37
AppearanceWhite to off-white powder
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Product details

SB-408124 is a elective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). A critical role for the orexin-1 receptor (OX1R) in complex emotional behavior is emerging, such as overactivation of the OX1R pathway being associated with panic or anxiety states.

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