(6-((5-氟-2-((3,4,5-三甲氧基苯基)氨基)嘧啶-4-基)氨基)-2,2-二甲基-3-氧代-2H-吡啶并[3,2-b][1,4]恶嗪-4(3H)-基)甲基磷酸钠;福他替尼二钠盐
Fostamatinib Disodium;R788 Disodium
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Product Name Fostamatinib Disodium;R788 Disodium
CAS1025687-58-4
FormulaC23H24FN6Na2O9P
MW624.42
MDLMFCD15146370
AppearanceWhite to yellow powder
Storage condition4°C, sealed storage, away from moisture | In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

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Fostamatinib Disodium;R788 Disodium