| Product Name | Fostamatinib Disodium (Synonyms: R788 Disodium) |
|---|---|
| CAS | 1025687-58-4 |
| Formula | C23H24FN6Na2O9P |
| MW | 624.42 |
| MDL | MFCD15146370 |
| Appearance | White to yellow powder |
| Storage condition | 4°C, sealed storage, away from moisture | In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
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