凡德他尼
Vandetanib (Synonyms: ZD6474)
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
25 mg 50 mg 100 mg 250 mg 500 mg
Product Availability
In-stock
Price
$300.00
Member price
Product Availability
In-stock
Price
$400.00
Member price
Product Availability
In-stock
Price
$500.00
Member price
Product Availability
In-stock
Price
$900.00
Member price
Product Availability
In-stock
Price
$1500.00
Member price
Quantity
- +
Product Overview
Product Name Vandetanib (Synonyms: ZD6474)
CAS443913-73-3
FormulaC22H24BrFN4O2
MW475.35
AppearanceWhite Powder
Security information
Product details

Vandetanib is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay. It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM, respectively. Not sensitive to PDGFRβ, Flt1, Tie-2 and FGFR1 with IC50 of 1.1-3.6 μM. No activity against MEK, CDK2, c-Kit, erbB2, FAK, PDK1, Akt and IGF-1R with IC50 above 10 μM. Vandetanib (ZD6474) increases apoptosis and induces autophagy by increasing the level of reactive oxygen species (ROS).
Tags: buy Vandetanib | Vandetanib supplier | purchase Vandetanib | Vandetanib cost | Vandetanib manufacturer | order Vandetanib | Vandetanib distributor

Related literature
Related
Sorry, no related items
History
Vandetanib (Synonyms: ZD6474)