LY2109761
LY2109761
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name LY2109761
CAS700874-71-1
FormulaC26H27N5O2
MW441.52
AppearanceWhite to yellow powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
Security information
Product details

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagy and induces apoptosis.


Related literature
Related
Sorry, no related items
History
LY2109761