Timapiprant Sodium (OC000459 Sodium)
Timapiprant Sodium (Synonyms: OC000459 Sodium)
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Product Name Timapiprant Sodium (Synonyms: OC000459 Sodium)
CAS950688-14-9
FormulaC21H16FN2NaO2
MW370.35
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Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

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