Product Name | Romidepsin (Synonyms: FK 228; FR 901228; NSC 630176) |
---|---|
CAS | 128517-07-7 |
Formula | C24H36N4O6S2 |
MW | 540.70 |
MDL | MFCD18433404 |
Appearance | White to off-white powder |
Romidepsin (FR 901228) is an HDAC inhibitor targeting HDAC1/2/4/6 with IC50 values of 36/47/510/1400 nM. It has antitumor activity and is used to treat peripheral and cutaneous T-cell lymphomas.Romidepsin (FK 228), derived from Chromobacterium violaceum, induces G2/M cell cycle arrest and apoptosis.
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