环索奈德
Ciclesonide (RPR251526)
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
5 mg 10 mg 25 mg 50 mg
Product Availability
In-stock
Price
$220.00
Member price
Product Availability
In-stock
Price
$350.00
Member price
Product Availability
In-stock
Price
$550.00
Member price
Product Availability
In-stock
Price
$860.00
Member price
Quantity
- +
Product Overview
Product Name Ciclesonide (RPR251526)
CAS126544-47-6
FormulaC32H44O7
MW540.69
AppearanceWhite-like crystalline powder
Security information
Product details

Ciclesonide (CIC) is a prodrug form of the glucocorticoid receptor agonist desisobutyryl-CIC (des-CIC). CIC binds to the glucocorticoid receptor with a Ki value of 37 nM. It is selective for the glucocorticoid receptor over the estrogen, progesterone, and testosterone receptors. CIC inhibits eosinophil influx into the lung (ED50 = 0.49 mg/kg) and reduces sephadex-induced lung edema (ED50 = 0.72 mg/kg) in a rat model of ovalbumin-sensitized and -challenged airway inflammation. Formulations containing CIC have been used in the maintenance treatment of asthma and in the treatment of allergic rhinitis.

Related literature
Related
Sorry, no related items
History
Cynaroside | Luteolin 7-O-glucoside | Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside
Linarin;Acaciin; Buddleoside
Canagliflozin
Ciclesonide (RPR251526)
Anti-Human CD3ExCD20 (Epcoritamab; GEN3013)
Thunberginol C
Skullcapflavone I | Panicolin
Sinapaldehyde
Mal-C6-amine TFA
Santamarine | Balchanin | Santamarin