| Product Name | CP-547632 (Synonyms: PAN-90806; CP-632; OSI-632) |
|---|---|
| CAS | 252003-65-9 |
| Formula | C20H24BrF2N5O3S |
| MW | 532.40 |
| MDL | MFCD07772279 |
| Appearance | White to light yellow powder |
| Storage condition | 4°C, stored under nitrogen |
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
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