Product Name | CP-547632 | PAN-90806 | CP-632 | OSI-632 |
---|---|
CAS | 252003-65-9 |
Formula | C20H24BrF2N5O3S |
MW | 532.40 |
MDL | MFCD07772279 |
Appearance | White to light yellow powder |
Storage condition | 4°C, stored under nitrogen |
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
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