两性霉素 B
Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
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Product Overview
Product Name Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
CAS1397-89-3
FormulaC47H73NO17
MW924.09
AppearanceYellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.

Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration.
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History
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Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
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