氯氮平N-氧化盐酸
Clozapine N-oxide dihydrochloride
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Product Overview
Product Name Clozapine N-oxide dihydrochloride
CAS2250025-93-3
FormulaC18H19ClN4O · 2HCl
MW415.74 | 342.83(free)
AppearanceLight yellow to yellow powder
Storage condition 4°C, stored under nitrogen
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Product details

Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.


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Clozapine N-oxide
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