Product Name | Clozapine N-oxide dihydrochloride |
---|---|
CAS | 2250025-93-3 |
Formula | C18H19ClN4O · 2HCl |
MW | 415.74 | 342.83(free) |
Appearance | Light yellow to yellow powder |
Storage condition | 4°C, stored under nitrogen |
Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.
© Copyright 2015-2021 Chemleader Biomedical Co., Ltd. All Rights Reserved.
沪ICP备15046197号-4
沪公网安备31011502007856号
Designed by Kuanersoft