阿氟色替
Afuresertib | GSK2110183 | LAE002
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Product Overview
Product Name Afuresertib | GSK2110183 | LAE002
CAS1047644-62-1
FormulaC18H17Cl2FN4OS
MW427.32
AppearanceWhite to off-white powder
Storage condition-20°C, protect from light, stored under nitrogen
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Product details

Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively.


Related literature
Related
Afuresertib-F HCl | GSK2110183-analog 1 HCl |
Afuresertib-F free base | Afuresertib-F free base | GSK-2110183-analog 1
Afuresertib HCl | Afuresertib hydrochloride | GSK2110183 hydrochloride | LAE002 hydrochloride
History
ABT-737
Afuresertib | GSK2110183 | LAE002
Carfilzomib (Synonyms: PR-171)
Werner syndrome RecQ helicase-IN-1 sodium (EX-A7900;G65952); N-(2-Chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide, sodium salt
sulfo-SPDB-DM4