| Product Name | Lubiprostone (Synonyms: RU-0211; SPI-0211) |
|---|---|
| CAS | 136790-76-6 |
| Formula | C20H32F2O5 |
| MW | 390.46 |
Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
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