(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-羟基-5,6-二甲基庚-3-烯-2-基)-7-甲基八氢-4H-茚-4-亚基)亚乙基)环己烷-1,3-二醇 ;帕立骨化醇
Paricalcitol
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Product Overview
Product Name Paricalcitol
CAS131918-61-1
FormulaC27H44O3
MW416.64
MDLMFCD08067734
AppearanceWhite to off-white powder
Storage condition4°C, protect from light, stored under nitrogen
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Paricalcitol, a selective VDR agonist, effectively suppresses PTH mRNA and inhibits parathyroid cell growth, treating secondary hyperparathyroidism in CKD. It's also associated with lower morbidity and improved survival rates compared to other VDRAs, with a favorable side-effect profile. Additionally, paricalcitol exhibits anti-inflammatory effects, potentially beneficial in managing CKD-related inflammation.


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Paricalcitol