陶扎色替
Tozasertib(VX-680;MK-0457)
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
25 mg 50 mg 100 mg 500 mg
Product Availability
In-stock
Price
$300.00
Member price
Product Availability
In-stock
Price
$450.00
Member price
Product Availability
In-stock
Price
$550.00
Member price
Product Availability
In-stock
Price
$2200.00
Member price
Quantity
- +
Product Overview
Product Name Tozasertib(VX-680;MK-0457)
CAS639089-54-6
FormulaC23H28N8OS
MW464.59
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

Tozasertib (VX-680) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM in a cell-free assay, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. The only exceptions are Fms-related tyrosine kinase-3 (FLT-3) and BCR-ABL tyrosine kinase, which are inhibited by the Tozasertib with both Ki of 30 nM. Tozasertib induces apoptosis and autophagy.  

Related literature
Related
Sorry, no related items
History
Dipeptide Diaminobutyroyl Benzylamide Diacetate; β-Ala-Pro-Dab-NHBn .2Acetate
Irinotecan Hydrochloride Trihydrate (Synonyms: Irinotecan (CPT-11) HCl Trihydrate;(+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate;lrinotecan HCl Trihydrate)
Enfuvirtide Acetate (Synonyms: T20 Acetate; DP178 Acetate;T-20 Acetate)
Tozasertib(VX-680;MK-0457)
Fmoc-D-Thr(tBu)-OH/N-Fmoc-O-tert-butyl-D-threonine
Tariquidar dihydrochloride | XR9576 dihydrochloride
Carbidopa monohydrate | (S)-(-)-Carbidopa monohydrate
Recombinant Human DES (1-3) Insulin-like Growth Factor-1 [rHuDes (1-3) IGF-1]
Sivelestat Sodium Anhydrous | ONO5046-Na | Sodium sivelestat | EI546 sodium | LY544349 sodium
SRT 1720 dihydrochloride