N-(4-甲基-3-((4-(吡啶-3-基)嘧啶-2-基)氨基)苯基)-4-((4-甲基哌嗪-1-基)甲基)苯甲酰胺甲磺酸盐;甲磺酸伊马替尼
Imatinib Mesylate (Synonyms: STI571 Mesylate; CGP-57148B Mesylate)
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Product Name Imatinib Mesylate (Synonyms: STI571 Mesylate; CGP-57148B Mesylate)
CAS220127-57-1
FormulaC30H35N7O4S
MW589.71
MDLMFCD04307699
AppearanceWhite or almost white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Imatinib Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Ablc-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.

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History
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