N-(2-氯-6-甲基苯基)-2-((6-(4-(2-羟乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)氨基)噻唑-5-甲酰胺; 达沙替尼
Dasatinib (Synonyms: BMS-354825)
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Product Name Dasatinib (Synonyms: BMS-354825)
CAS302962-49-8
FormulaC22H26ClN7O2S
MW488.01
MDLMFCD11046566
AppearanceWhite, off-white to pale yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Dasatinib is a novel, potent and multi-targeted inhibitor that targets AblSrc and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.

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History
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