Product Name | Dasatinib (Synonyms: BMS-354825) |
---|---|
CAS | 302962-49-8 |
Formula | C22H26ClN7O2S |
MW | 488.01 |
MDL | MFCD11046566 |
Appearance | White, off-white to pale yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
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