培美曲赛二钠七水合物
Pemetrexed Disodium Heptahydrate (Synonyms: LY231514 disodium heptahydrate)
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500 mg 1 g 5 g
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In-stock
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$125.00
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In-stock
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$200.00
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$320.00
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Product Overview
Product Name Pemetrexed Disodium Heptahydrate (Synonyms: LY231514 disodium heptahydrate)
CAS357166-29-1
FormulaC20H33N5Na2O13
MW597.48
AppearanceWhite to off-white powder
Storage condition4°C, sealed storage, away from moisture
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Product details

Pemetrexed disodium heptahydrate (LY231514; HSDB7316; LY-231514; HSDB-7316; Alimta), the heptahydrated disodium salt of Pemetrexed and a pyrimidine-based antifolate, is an antifolate and antimetabolite anticancer medication. It targets TS, DHFR, and GARFT with Ki values of 1.3 nM, 7.2 nM, and 65 nM, in that order. In a variety of tumor types, including malignant mesothelioma, NSCLC (non-small cell lung carcinoma), carcinomas of the breast, colorectum, uterine cervix, head and neck, and bladder, pemetrexed shows strong antitumor activity.
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