Product Name | Teniposide (Synonyms: VM26) |
---|---|
CAS | 29767-20-2 |
Formula | C32H32O13S |
MW | 656.66 |
MDL | MFCD00866516 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Teniposide is a semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose-dependent single- and double-stranded breaks in DNA, DNA: protein cross-links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle.
© Copyright 2015-2021 Chemleader Biomedical Co., Ltd. All Rights Reserved.
沪ICP备15046197号-4
沪公网安备31011502007856号
Designed by Kuanersoft