二盐酸诺拉曲塞
Nolatrexed dihydrochloride
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
5 mg 10 mg 20 mg 50 mg
Product Availability
In-stock
Price
$400.00
Member price
Product Availability
In-stock
Price
$600.00
Member price
Product Availability
In-stock
Price
$1100.00
Member price
Product Availability
In-stock
Price
$1650.00
Member price
Quantity
- +
Product Overview
Product Name Nolatrexed dihydrochloride
CAS152946-68-4
FormulaC14H14Cl2N4OS
MW357.26
Appearance Light yellow to yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication,  DNA damage,S-phase cell cycle arrest, and caspase-dependent apoptosis.This agent also exhibits radiosensitizing activity.


Related literature
Related
Sorry, no related items
History
Etanercept,stock solution
Rimonabant Hydrochloride
Nolatrexed dihydrochloride
Tremelimumab (anti-CTLA-4)
DM4
Galunisertib monohydrate | LY2157299 monohydrate
Urelumab (Anti-TNFRSF9 / 4-1BB / CD137)